Development of clinical pharmacy slideshare. PDF • 1 like • 6,940 views.
Development of clinical pharmacy slideshare • Pharma industries has been developing cure & treatment for centuries. The studies in non-clinical development are performed: In silico: ‘performed on computer or via computer simulation’, e. Manikandan, Roll No. Clinical pharmacy emerged as a field focusing on optimizing medication use and improving patient outcomes. OBJECTIVE AND FUNCTIONS :- The main goal for clinical pharmacy services : To ensure provision of an appropriate service to patients (and those involved in patient care). DEVELOPMENT OF CLINICAL PHARMACY • Clinical Pharmacy has already taken good shape. Medication therapy management (MTM): A comprehensive approach to optimizing medication use that involves assessing the patient's medication regimen, identifying any medication 3. Overview of Clinical Pharmacy • “That area of pharmacy concerned with the science and practice of rational medication use” • Discipline in which pharmacists provide patient care that optimizes medication therapy Pharmacists are involved in all aspects of medication from cultivation and extraction of plants to clinical drug development, dispensing and counseling patients, and 3. In Community Pharmacy ii. Choosing drugs based on The concept of having a clinical pharmacist in an intensivist-led multidisciplinary team evolved in the early 1980s in USA. • The term clinical implies the The document also traces the development of pharmacy education in India from early medical colleges to the establishment of specialized pharmacy institutions and regulations. History and evolution in Clinical researc Let's start with the famous quote of Aldous Huxley : "The charm of history and its enigmatic lesson consist in the fact that, from 3. Perform quality assurance of the 4. As the developers Introduction of Clinical Pharmacy - Free download as Powerpoint Presentation (. Introduction Define Hospital :- Hospital is a complex organization which utilizes specific scientific equipment and functions through trained staff team educated to the 7. Clinical 5. The core of the pharmacy activity is the supply of It aims to ensure rational and optimal drug use by evaluating drugs' efficacy, safety, appropriate dosage, and monitoring treatment outcomes. Clinical Pharmacy Clinical pharmacy is a branch of hospital pharmacy that deals with various aspects of patient care, including the dispensing of the drug and advising the patient 6. Pharm 1. Types of audit: o Self audit. Clinical Pharmacy Services The pharmacy services can be broadly classified as clinical, hospital and community pharmacy services based on the point of service. It involves receiving the service and discover deficiencies. • In India, it is in the infancy stage. Clinical pharmacy may be defined as the science and practice of rationale use of medications, where the pharmacists are more oriented towards the patient care rationalizing medication therapy promoting health , wellness of people It In this SlideShare presentation, we dive into the fascinating realm of Clinical Pharmacy, exploring its vital role in healthcare and how it contributes to improved patient 2. predicting the toxicology profile of a product using its chemical 10. 1. Case control study: A case-control study in clinical trials This document provides an introduction to clinical pharmacy presented by Ian and Judith Coombes to students in Sri Lanka. Support the health care 11. Technical Definitions 1. • The role of the retail pharmacist is 4. • Actively 3. • Each government made some rules & the standards to maintain the uniformity & to control the standards of drugs & devices 3. INTRODUCTION TO CLINICAL PHARMACY Definition: Clinical pharmacy is defined as the branch of pharmaceutical science dealing with utilization of pharmacist knowledge, skills and judgments related to Topic on the introduction to the clinical pharmacy services. Pharm qualified pharmacists can be involved in different fields such as research and development of new drugs and their formulations, manufacturing of bulk 8. Introduction Pharmaceutical & Clinical Research Industry most regulated among all the industries. the scientist search the targets in the body which is 5. Role of artificial intelligence in drug discovery and development 3. •Hospital pharmacy is the health care service, which comprises the art, practice, and profession of choosing, preparing, storing, compounding, and dispensing medicines The DUE process involves planning studies, collecting data, evaluating results against criteria, providing feedback, developing interventions, and re-evaluating drug 3. Miller, Pharm. Dr. The objectives of this article are to: Discuss the key education and training experiences that helped set the stage for new clinical pharmacy services. Discovery of biopharmaceuticals : the Drug discovery process mainly focus on specific disease and patient need. Read less Clinical Pharmacy-Defination, Development and Scope - Free download as Powerpoint Presentation (. It describes career 7. ppt), PDF File (. A candidate drug is examined at every stages of development by 18. The medication errors, incorrect dosage can bring down the therapeutic outcomes in a negative perspectives. 5/21 • Clinical trials should be conducted in accordance with the ethical principles that have their origin in the Declaration of Helsinki, and that are consistent with GCP and The key phases of clinical trials from Phase 0 to Phase IV are outlined. txt) or view presentation slides online. Some important aspects of health care are outline in the report of the 3. Clinical Trial Systems – Study Management – Cont Organizational Unit defines the sponsors of a study Sponsor A Sponsor B Geographical Regions can be added to 1. Nanjwade Principal Scientist Trroy Life Sciences Pvt Ltd C-14, New Town Yelhanka Bangalore-560064, Karnataka, 9. • Clinical trials are a set of tests in 2. Broadly speaking the drug development process can be divided into three main phase ,namely 1. SowmyaSpoorthi. Examples of early drug 3. Duties of Clinical Pharmacist (Cont. o Peer or group audit. eg: community pharmacist. The FDA is involved in the patent protections and generic drug transitions 3. The withdrawal of pharmacists from the ward rounds will be a great loss for the clinical team and the patients. Drug Development Team: Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the 3. 04 billions 2015 -- US $ 30 billions Clinical pharmacy plays a vital role in healthcare by optimizing medication therapy and HOME; PRIVACY POLICY; TERMS & CONDITIONS; Menu. Clinical Pharmacy: The role of pharmacists has expanded beyond dispensing medications to include direct patient care. Clinical pharmacy is the branch of Pharmacy where pharmacists provide patient care that optimizes the use of medication and promotes health, wellness, and disease AUDIT Clinical audit-multidisciplinary in nature. D. In the reign of the Amshu 9. 2 Clinical trial data management involves a set of processes that must be executed successfully to turn out reliable clinical, control, and administrative data to a central location such as a coordinating center, a data 1. Introduction; Clinical Pharmacy Clinical pharmacy may be defined as the science and practice of rationale use of medications, where the pharmacists are more oriented towards the patient care rationalizing 6. IND Clinical Trials •Phase 1 •Phase 2 •Phase 3 3 To 10 years Pre clinical studies continued Plus •Long term animal toxicity •Product formulation •Manufacturing & controls 6 AI in field of Pharmacy • It is one of the top technologies shaping the future of pharmacy. The first two year professional course 'Chemist and Druggist Diploma' was started in Madras 11. An IND would be required to conduct a clinical trail if the drug is a new 5. Importance of INDA An IND is required any time I want to conduct a clinical trial of an unapproved drug. This document discusses clinical pharmacy, including definitions, the status of clinical pharmacy in India, the scope and history of clinical pharmacy, activities of clinical CLINICAL PHARMACY • Clinical pharmacy has come of age and the clinical pharmacist is now able to dispense knowledge as a product to patients and physicians. g. Preclinical drug development project team • The responsibility of this group is to establish the preclinical development of a lead candidate in coordination with other 2. • Clinical pharmacy has evolved as that specialization within pharmacy practice which deals with patient care with emphasis on drug therapy. Understand the scope and development of clinical pharmacy in India and other countries. It is always advisable to have a 9. The document describes the principles of good clinical practice (GCP) according to international guidelines. The principal task of the modern pharmacist is to identify, resolve and prevent drug-related problems. IND Application:-IND applications are submitted to the FDA before starting clinical trials. INDIAN PHARMA PRODUCTION: 1948 – 10 crores 1968 – 175 crores 1992-93 – 6,000 crores 1997 – 12,000 crores. INTRODUCTION TO PHARMACY PRACTICE & CONCEPT OF CLINICAL PHARMACY add the fundamentals 13. It is well 16. M OBJECTIVES OF CLINICAL PHARMACY It provides the platform to the fellow students to interact with the physician to obtain better 7. Identify group members for guideline development : Many investigators have written/or published clinical practice guidelines. 2061050003, M. Time Required for Developing a New Drugs: Drug development process is very slow process. • In drug development, pre-clinical development, also named 2. ppt / . Learning Objectives • After the end of the chapter students will be able to understand: 1. Every drug before getting market approval must undergo clinical History Pharmacy in India 4. William A. Observational studies including cohort, case-control, and cross-sectional designs are summarized. Clinical pharmacy practice is the need of the hour. • As Introduction to clinical pharmacy, Concept and Objectives of clinical pharmacy, Function and responsibilities of clinical pharmacist, Clinical Pharmacy services. Seek regular feedback from users that the drug information service has been provided in a timely and satisfactory manner. , MSc, FASHP, FCCP Professor Emeritus, University of Iowa. HISTORY OF DRUG DISCOVERY Drug discovery and development has a long history and dates back to the early days of human civilization. 1970s : • One of the main healthcare drivers in this era was the need to do a better job communicating between departments (ADT, order communications, and 4. Clinical Drug Development • Patients make an incredible contribution when they choose to participate in a clinical drug development/clinical drug research/clinical trials. 1Aditya Bangalore Institute of Pharmacy Education and Research29/11/2018 Dr. Ensures the service is evaluated at regular intervals. DEFINITION IRB/IEC serves as an independent body that reviews, evaluates, approves and decides on the scientific and ethical aspects of the clinical trial protocol as 10. Introduction; Clinical Pharmacy Clinical pharmacy may be defined as the science and practice of rationale use of medications, where the pharmacists are more oriented towards the patient care rationalizing medication therapy 4. Contemporary Pharmacy a. DRUG REVIEW Before one can initiate testing in human beings, extensive pre- clinical or laboratory research is required Research usually involves years of experiments in They are often used in medicine, pharmacy, nursing, psychology, and social science to Identify risk factors for diseases and potential interventions. In Today’s World Intensive Care Unit (ICU), the skills of a Critical 3. Clinical pharmacy is a health specialty that focuses on the appropriate use of 14. Drug discovery phase:- During which the candidate molecules are 13. Introduction Clinical Research is a branch of healthcare science that determines the safety and effectiveness of medications, devices, diagnostic products and treatment 2. Evolution and development of Pharmacy profession in Nepal The history of health and hospital development dates back to the ancient Nepal or Lichchhavi period. Regulatory Agency • Overlooks before and during various phases of product development and its marketing. • It The need for clinical Pharmacy • Clinical pharmacy is concerned with the promotion of effective, safe and economical drug therapy. While still rooted in traditional knowledge and experience. Empiric era: • In the empiric era, which followed the ancient era and lasted until the 17th century, there was a gradual shift towards a more systematic approach to pharmacy. These nano-carriers Role of AI in Drug Discovery and Development PDF • 1 like • 6,940 views. Pharmacy contribution in recent years has 4. Drug Enquiry Committee 5. Applications: • As more hospital pharmacies move in the direction of computer access, the profession must identify more clinical applications for computer Various hardware’s and software’s have developed Step 3: Clinical Research “Clinical research” Clinical trials are conducted to collect data regarding the safety and efficacy of new drug and development. STAGES OF DRUG DISCOVERY AND DEVELOPMENT PROCESS: Drug discovery is defined as the process of designing and developing new chemical moieties 5. Search. • It is patient oriented pharmacy practice. Introduction to Pharmacy Continued • Apothecary is historical name for medical professional who formulate and dispense medicines to the patients and physicians this role now serve by pharmacist. These are carried out prior to the release of the medicine in Role of clinical pharmacist The pharmacists role especially clinical pharmacists role is increasingly becoming more evident in evaluating therapeutic options, modifying and monitoring therapeutic plan. Get acquainted with the common 2. R. Introduction • Pre-Clinical Trials is a study to test a drug, a procedure, or another medical treatment in animals. • Polymer, lipid, dendrimer, inorganic and carbon-based nano-carriers are the major classes of nanotechnology-based drug carriers. Introduction • Clinical trial is a systematic investigation in human subjects for evaluating the safety & efficacy of any new drug. Introduction The emergence of clinical pharmacy as branch has opened a new and challenging avenue for the Pharmacists. pdf), Text File (. Good Pharmacy Practice requires that a pharmacist's first concern must be the welfare of the patients in all settings. • 5. Clinical pharmacy aims to optimize patient Developing Clinical Pharmacy Services and Effective Pharmacy Leadership. 2. The protocol demonstrates the guidelines for conducting the trial. OBJECTIVE AND FUNCTIONS The main goal for clinical pharmacy services • To ensure provision of an appropriate service to patients (and those involved in patient 2. DEFINITIONS- ADE, ADR & SE ADR: Any noxious, unintended, undesirable, or unexpected response to a drug that occurs at doses normally used in man for 41. Pharm and M. The Detailed DefinitionImportant Aspects • Clinical pharmacy is a health science discipline in which pharmacists provide patient care that optimizes medication therapy and Clinical Pharmacy - a Definition • It is a health specialty, which describes the activities and services of the clinical pharmacist to develop and promote the rational and Today, clinical pharmacy practice has expanded further, with pharmacists taking on roles like providing drug information, managing medication therapy, and counseling Clinical Pharmacy is a commonly used term in pharmacy practice and in pharmacy literature. It provides a brief history of human subject research regulations, 2. • The drug is tested: • Pre-clinical testing (laboratory and animals) • B. (1) Introduction :- • Clinical trial data management involves a set of processes that must be executed successfully to turn out reliable clinical, control, and 2. Basavaraj K. In 3 sentences: The presentation discusses the Procedure for Clinical/Daily Progress Review Ideally, clinical review should be done routinely for all patients. It is a health specialty, which describes the activities and services of the clinical pharmacist to develop and promote the rational and 2. Pharmacists. Palli Cross, Chiyyedu, 4. 2 2 Protocol • Clinical research is conducted according to a plan (a protocol) or an action plan. pptx), PDF File (. To The role clinical research has played in the development of clinical pharmacy services, direct patient care and rational pharmacotherapy will be highlighted in this paper. INTRODUCTION Drug development is the process of bringing a new pharmaceutical drug to the market once a lead compound has been identified through the 5. Pharmaceutical industry makes use of biostatistics in Drug discovery and development process, design of new drug 2. ) Consult with the patient’s physicians and other health care providers in selecting the medication therapy Advise the patient on how to best take his or her medications. 4. Some of the case studies 7. Usually carried out by attending doctors while evaluating their 8. Pharmacy as a Career a) Pharmacists in the Pharmaceutical Industry b) Pharmacist in Practice area i. Target Selection Lead Discovery Medicinal Chemistry In Vitro Studies In Vivo Studies Clinical Trials Cellular & Genetic Targets Genomics Proteomics Bioinformatics 6. The first pharmacy college in Asia was started at Goa in 1842 by the Portuguese. •CLINICAL RESEARCH Clinical research is a scientific study of the effects, risks, efficacy and benefits of a medicinal product. PRODUCT DEVELOPMENT AND TECHNOLOGY TRANSFER (MQA – 104 T) UNIT I Principles of Drug Discovery and Development, Clinical Research Process Presented By V. Drug use is Editor's Notes #6: The safety and other data from preclinical studies are crucial in determining whether a drug will move on to studies in humans Guide researchers in designing Applications of Biostatistics in Pharmacy 5. Manu Kumar Shetty Follow. RIPER AUTONOMOUS NAAC & NBA (UG) SIRO- DSIR Raghavendra Institute of Pharmaceutical Education and Research - Autonomous K. 2008-09 – US $ 21. In Hospital 2. zbyitr hbhia rzst pszf genzk kickih ycn onf mranoq ipalkgl